22:15-19 There are high declarations of God's favour to Abraham in this confirmation of the covenant with him, exceeding any he had yet been blessed with. Those that are willing to part with any thing for God, shall have it made up to them with unspeakable advantage. The promise, ver. 18, doubtless points at the Messiah, and the grace of the gospel. Hereby we know the loving-kindness of God our Saviour towards sinful man, in that he hath not withheld his Son, his only Son, from us. Hereby we perceive the love of Christ, in that he gave himself a sacrifice for our sins. Yet he lives, and calls to sinners to come to him, and partake of his blood-bought salvation. He calls to his redeemed people to rejoice in him, and to glorify him. What then shall we render for all his benefits? Let his love constrain us to live not to ourselves, but to Him who died for us, and rose again. Admiring and adoring His grace, let us devote our all to his service, who laid down his life for our salvation. Whatever is dearest to us upon earth is our Isaac. And the only way for us to find comfort in an earthly thing, is to give it by faith into the hands of God. Yet remember that Abraham was not justified by his readiness to obey, but by the infinitely more noble obedience of Jesus Christ; his faith receiving this, relying on this, rejoicing in this, disposed and made him able for such wonderful self-denial and duty.That in blessing I will bless thee,.... With temporal and spiritual blessings; with the Spirit and all his graces; with Christ and redemption, justification, and salvation by him; and with eternal life, as the gift of God, through him:

and in multiplying I will multiply thy seed as the stars of the heaven, and as the sand which is upon the sea shore: both his natural seed, descending from him in the line of Isaac, and his spiritual seed, both among Jews and Gentiles, that tread in his steps; see Genesis 13:15,

and thy seed shall possess the gate of his enemies: "gate" for "gates", where courts of judicature were held, and which are the security of cities and put for them, and which also include the whole country round about: so that this phrase is expressive of an entire jurisdiction and dominion over them; and was literally fulfilled in the times of Joshua, David, and Solomon; and spiritually in Christ, Abraham's principal seed, when he destroyed Satan and his principalities and powers; overcame the world; made an end of sin and abolished death; and delivered his people out the hands of all their enemies; and in all Abraham's spiritual seed, who are made more than conquerors over them, through Christ that has loved them.