(25) Have an issue . . . many days.--The last case is that of a chronic issue, arising from a derangement in the constitution. This is the kind of complaint from which the woman suffered who came to Christ (Matthew 9:20; Luke 8:44). As long as she suffered from it, which lasted sometimes for many years, she defiled and was defiling in the same way as in her menses.

Verses 25-30. - The fifth case of an issue - that of excessive menstruation, or menstruation occurring at the wrong time. This was probably the disease of the woman "who had an issue of blood" (Matthew 9:20; Mark 5:25; Luke 8:43).

15:1-33 Laws concerning ceremonial uncleanness. - We need not be curious in explaining these laws; but have reason to be thankful that we need fear no defilement, except that of sin, nor need ceremonial and burdensome purifications. These laws remind us that God sees all things, even those which escape the notice of men. The great gospel duties of faith and repentance are here signified, and the great gospel privileges of the application of Christ's blood to our souls for our justification, and his grace for our sanctification.And if a woman have an issue of her blood many days out of the time of her separation,.... Not an ordinary but an extraordinary one, not within that time, but out of it, and which continued three days at least; so the Targum of Jonathan, and sometimes many years; as the poor woman Christ cured, which she had had twelve years; see Gill on Matthew 9:20,

or if it run beyond the time of her separation; beyond the seven days of her separation, and so out of the usual way and time of it; whereby it appears to be somewhat extraordinary and unusual:

all the days of the issue of her uncleanness shall be as the days of her separation: all the while it was upon her, be it ever so many days or years, she was kept apart from her husband, and in all respects in the same condition and circumstances, as in the seven days of her separation because of her monthly courses:

she shall be unclean; as long as it is upon her, and neither be admitted to her husband's bed, nor to the house of God, which made her condition a very deplorable one.